2021/07 ~ 2024/06：乳品供应链中病原菌的快速检测和控制新技术研究；项目类别：国家重点研发计划；项目来源：科技部。

2021/04 ~ 2024/04：休闲食品安全危害物检测新技术及加工新技术开发；项目类别：企业项目；项目来源：企业委托。

2021/12 ~ 2022/11：配方乳粉中真菌毒素和致病菌的检测服务与乳制品中危害物控制新技术服务；项目类别：企业项目；项目来源：企业委托。

2021.07 ~ 2022.07：益生菌高蛋白发酵乳的研究与开发；项目类别：企业项目；项目来源：企业委托。

2021/03 ~ 2021/12：高邮食品产业园产业发展规划编制；项目类别：企业项目；项目来源：企业委托。

2021/03 ~ 2026/03：汉唐子苏系列产品技术服务：项目类别：企业项目；项目来源：企业委托。

2020/08 ~ 2020/12：一种蛋白酶制剂的产品研发；项目类别：企业项目；项目来源：企业委托。

2019/07 ~ 2021/06：多种真菌毒素同时降解用食品级酵母菌的构建技术创新及产品创制；项目类别：江苏省农业科技自主创新资金；项目来源：江苏省财政厅/江苏省农业科学院。

2018/07 ~ 2020/06：生猪养殖与屠宰废弃物资源化利用技术创新与应用；项目类别：江苏省苏北科技专项/企业项目；项目来源：江苏省科技厅。

2018/03 ~ 2019/06：马铃薯提取物加工工艺开发；项目类别：企业项目；项目来源：企业委托。

2016/09 ~ 2017/09：江苏省高校优秀中青年教师和校长境外研修资助项目；项目类别：出国研修计划；项目来源：江苏省教育厅

2015/04 ~ 2018/03：腌制水产品亚硝酸盐或胺类物质的控制技术研究；项目类别：国家科技支撑计划；项目来源：科技部。

2018/01 ~ 2022/12：食品危害物核酸适配体-靶标结合机制研究；项目类别：国家自然科学基金；项目来源：国家自然科学基金委员会，参加。

2012/01 ~ 2014/12：食品非法添加物高通量筛查技术与装备研究；项目类别：国家科技支撑计划；项目来源：科技部，参加。

2011/01 ~ 2013/12：耐热β-半乳糖苷酶在枯草芽孢杆菌中分泌效率的限制因素研究；项目类别：国家自然科学基金；项目来源：国家自然科学基金委员会。

2009/01 ~ 2011/12：食品酶在枯草芽孢杆菌中以Tat途径分泌时前体加工效率的影响因素；项目类别：教育部博士点基金；项目来源：教育部。

2008/07 ~ 2011/06：耐热β-半乳糖苷酶在枯草芽孢杆菌中分泌效率的限制因素研究；项目类别：江苏省自然科学基金；项目来源：江苏省科技厅。

2006/12 ~ 2010/10：枯草芽孢杆菌多适性食品级表达系统构建及分泌途径改造；项目类别：863项目；项目来源：科技部；参加。

Xinling Du, Mumin Zheng, Han Zhang, Yangyu Qiu, Fuchun Ji, Zishen Nie, Huidong Xu, Xiaoxuan Li, Shijia Wu, Zhouping Wang, Fuguo Xing*, Yu Xia*. 2025. New application of a dye-decolorizing peroxidase immobilized on magnetic nanoparticles for efficient simultaneous degradation of two mycotoxins. Food Chemistry, 463:141341.

Han Zhang, Zhen Sun, Xinling Du, Qianqian Cheng, Fuchun Ji, Zishen Nie, Julei Zhan, Zhouping Wang, Aitao Li, Irina Delidovich, Yu Xia*. 2024. D-Allulose production via a simplified in vitro multienzyme cascade strategy: Biosynthesis and crystallization. Food Bioscience, 62:105507.

Ling Ji, Xinling Du, Han Zhang, Fuchun Ji, Zishen Nie, Yu Xia*. 2024. Establishment of a multiplex qPCR method for sensitive detection of proteolytic psychrotrophic bacteria in raw milk. Food Bioscience, 62:105339.

Zhen Sun, Yingxin You, Huidong Xu, Yang You, Wenjing He, Zhouping Wang, Aitao Li, Yu Xia*. 2024. Food-grade expression of two laccases in Pichia pastoris and study on their enzymatic degradation characteristics for mycotoxins. Journal of Agricultural and Food Chemistry, 72(16):9365-9375.

Yang You, Yangyu Qiu, Huidong Xu, Rui He, Lili Zhang, Zhouping Wang, Yu Xia*. 2024. Effective and food-grade detoxification of multiple mycotoxins using yeast expressed manganese peroxidases. Food Bioscience, 59:103886.

Huidong Xu, Qianqian Cheng, Yangyu Qiu, Jingjing Mao, Qinyi Ji, Mulan Zhu, Lili Zhang, Zhouping Wang, Aitao Li, Yu Xia*. 2023. A novel strategy for whole-cell biotransformation enabling simultaneous L‑phenyllactic acid production and coenzyme regeneration. Journal of Agricultural and Food Chemistry, 71(51):20772-20781.

Yangyu Qiu, Huidong Xu, Qinyi Ji, Rongrong Xu, Mulan Zhu, Yali Dang, Xizhi Shi, Lili Zhang, Yu Xia*. 2023. Mutation, food-grade expression, and characterization of a lactonase for zearalenone degradation. Applied Microbiology and Biotechnology, 107(16):5107-5118.

Yu Xia*, Zhe Zeng, Ana López Contreras, Chun Cui. 2023. Editorial: Innovative microbial technologies for future and sustainable food science. Frontiers in Microbiology, 14:1215775.

孙震, 程倩倩, 季勤怡, 朱钼蓝, 夏雨*[J]. 2023. D-阿洛酮糖的生物转化及冷却结晶工艺优化研究, 食品与发酵工业, 2023, 49(21):16-22.

Yu Xia*, Yangyu Qiu, Zifeng Wu, Qianqian Cheng, Xiuyu Hu, Xiaobing Cui and Zhouping Wang. 2022. Preparation of recombinant Kluyveromyces lactis agents for simultaneous degradation of two mycotoxins. AMB Express, 12:20.

Yu Xia*, Rui He, Yin Sun, Hangyu Zhou, Minjie Gao, Xiuyu Hu, Xiaobing Cui, Qianqian Cheng and Zhouping Wang. 2022. Food-grade expression of manganese peroxidases in recombinant Kluyveromyces lactis and degradation of aflatoxin B₁ using fermentation supernatants. Frontiers in Microbiology, 12:821230.

Yu Xia*, Zhi-Yuan Wei, Rui He, Jia-Huan Li, Zhi-Xin Wang, Jun-Da Huo and Jian-Huan Chen*. 2021. Hybrid de novo genome assembly of Erwinia sp. E602 and bioinformatic analysis characterized a new plasmid-borne lac operon under positive selection. Frontiers in Microbiology, 12:783195.

夏雨*, 吴梓凤, 胡修玉, 包红朵, 何瑞, 秋杨煜, 程倩倩, 王周平[J]. 2021. 同时降解两种真菌毒素的食品级重组酵母培养条件优化研究. 食品与发酵工业, 47(21):86-93.

Yu Xia*, Qianqian Cheng, Wanmeng Mu, Xiuyu Hu, Zhen Sun, Yangyu Qiu, Ximing Liu, Zhouping Wang. 2021. Research advances of D-allulose: An overview of physiological functions, enzymatic biotransformation technologies, and production processes. Foods, 10(9):2186.

Yu Xia*, Zifeng Wu, Rui He, Yahui Gao, Yangyu Qiu, Qianqian Cheng, Xiaoyuan Ma and Zhouping Wang. 2021. Simultaneous degradation of two mycotoxins enabled by a fusion enzyme in food-grade recombinant Kluyveromyces lactis. Bioresources and Bioprocessing, 8:62.

Yu Xia, Lili He, Jingjing Mao, Peipei Fang, Xiaoyuan Ma, Zhouping Wang*. 2018. Purification, characterization, and gene cloning of a new cold-adapted β-galactosidase from Erwinia sp. E602 isolated in northeast China. Journal of Dairy Science, 101(8):6946-6954.

Yukun Huang*, Xin Wang, Nuo Duan, Yu Xia, Zhouping Wang*, Xiao Yang, Xianggui Chen. 2018. Selection and characterization, application of a DNA aptamer targeted to Streptococcus pyogenes in cooked chicken. Analytical Biochemistry, 551: 37-42.

Xiaoyuan Ma, Xumin Xu, Yu Xia, Zhouping Wang. 2018. SERS aptasensor for Salmonella typhimurium detection based on spiny gold nanoparticles. Food Control, 84:232-237.

Yukun Huang, Xiujuan Chen, Yu Xia*, Shijia Wu, Nuo Duan, Xiaoyuan Ma, Zhouping Wang*. 2014. Selection, identification and application of a DNA aptamer against Staphylococcus aureus enterotoxin A. Analytical Methods, 6(3):690-697.

Xiaoyuan Ma, Yu Xia, Lili Ni, Liangjing Song, ZhoupingWang*. 2014. Preparation of gold nanoparticles-agarose gel composite and its application in SERS detection. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 121:657-661.

Jinglei Yuan, Zui Tao, Ye Yu, Xiaoyuan Ma*, Yu Xia, Li Wang, Zhouping Wang*. 2014. A visual detection method for Salmonella Typhimurium based on aptamer recognition and nanogold labeling. Food Control, 37:188-192.

夏雨, 王燕, 王周平*. 2013. 副溶血性弧菌(Vibrio parahaemolyticus)鞭毛蛋白FlaA的重组表达与多克隆抗体制备[J]. 食品与发酵工业, 39(11):18-22.

Jinglei Yuan, Ye Yu, Xiaoyuan Ma*, Yu Xia, Jie Chen, Zhouping Wang*. 2013. Visual detection and microplate assay for Staphylococcus aureus based on aptamer recognition coupled to tyramine signal amplification. Microchimica Acta, 181:321-327.

Guangqing Wang, Yu Xia, Jing Cui, Zhennan Gu, Yuanda Song, Yongquan Chen, Haiqin Chen*, Hao Zhang, Wei Chen*. 2013. The roles of moonlighting proteins in bacteria. Current Issues in Molecular Biology, 16(2):15-22.

Guangqing Wang, Haiqin Chen, Yu Xia, Jing Cui, Zhennan Gu, Yuanda Song, Yongquan Chen, Hao. Zhang*, Wei Chen*. 2013. How are the non-classically secreted bacterial proteins released into the extracellular milieu? Current Microbiology, 67(6):688-695.

Xiujuan Chen, Nuo Duan, Shijia Wu, Xiaoyuan Ma, Yu Xia, Changqing Zhu, Yuan Jiang, Zhouping Wang*. 2013. Selection and identification of ssDNA aptamers recognizing zearalenone. Analytical and Bioanalytical Chemistry, 405:6573-6581.

Nuo Duan, Shijia Wu, Xiujuan Chen, Yukun Huang, Yu Xia, Xiaoyuan Ma, Zhouping Wang*. 2013. Selection and characterization of aptamers against Salmonella typhimurium using whole-bacterium Systemic Evolution of Ligands by Exponential Enrichment (SELEX). Journal of Agricultural and Food Chemistry, 61:3229-3234.

Shijia Wu, Nuo Duan, Xiangli Li, Guiliang Tan, Xiaoyuan Ma, Yu Xia, Zhouping Wang*, Hongxin Wang. 2013. Homogenous detection of fumonisin B(1) with a molecular beacon based on fluorescence resonance energy transfer between NaYF4: Yb, Ho upconversion nanoparticles and gold nanoparticles. Talanta, 116:611-618.

Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Hongxin Wang, Zhouping Wang*. 2013. A highly sensitive fluorescence resonance energy transfer aptasensor for Staphylococcal enterotoxin B detection based on exonuclease-catalyzed target recycling strategy. Analytica Chimica Acta, 782:59-66.

Nuo Duan, Xiaoying Ding, Shijia Wu, Yu Xia, Xiaoyuan Ma, Zhouping Wang*, Jie Chen. 2013. In vitro selection of a DNA aptamer targeted against Shigella dysenteriae. Journal of Microbiological Methods, 94(3):170-174.

Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang*, Hongxin Wang. 2012. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as labels. Chemical Communications, 48(40):4866-4868.

Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Hongxin Wang, Zhouping Wang*, Qian Zhang*. 2012. Multiplexed fluorescence resonance energy transfer aptasensor between upconversion nanoparticles and graphene oxide for the simultaneous determination of mycotoxins. Analytical Chemistry, 84(14):6263-6270.

Yining Dong, Xiaoming Liu, Haiqin Chen, Yu Xia, Heping Zhang, Hao Zhang, Wei Chen*. 2011. Enhancement of the hydrolysis activity of β-galactosidase from Geobacillus stearothermophilus by saturation mutagenesis. Journal of Dairy Science, 94(3): 1176-1184.

Yu Xia. Purification and Characterization of A Novel Cold-adapted β-Galactosidase from A Newly Isolated Strain of Erwinia rhapontici. The 10th International Conference on Food Science and Technology. Number: KR12-06, Wuxi, China. 2013/05/30-31. Oral Presentation.

Yu Xia, Xiaoming Liu, Haiqin Chen, Hao Zhang, Wei Chen*. Construction of a signal peptide library for Bacillus subtilis and its application for secretory expression of a thermostable β-galactosidase. Asian Congress on Biotechnology 2011, Presentation Number: C1360, Shanghai, China. 2011/05/12-17. Poster

Yu Xia, Jianxin Zhao, Haiqin Chen, Xiaomin Liu, Yichuan Wang, Fengwei Tian, Heping Zhang, Hao Zhang, Wei Chen*. Extracellular secretion in Bacillus subtilis of a cytoplasmic thermostable β-galactosidase from Geobacillus stearothermophilus. Journal of Dairy Science, 2010, 93(7): 2838-2845.

Wei Chen*, Haiqin Chen, Yu Xia, Jing Yang, Jianxin Zhao, Fengwei Tian, Heping Zhang, Hao Zhang. 2009 Immobilization of recombinant thermostable β-galactosidase from Bacillus stearothermophilus for lactose hydrolysis in milk. Journal of Dairy Science, 92(2): 491-498.

Wei Chen*, Haiqin Chen, Yu Xia, Jianxin Zhao, Fengwei Tian, Hao Zhang. 2008. Production, purification, and characterization of a potential thermostable galactosidase for milk lactose hydrolysis from Bacillus stearothermophilus. Journal of Dairy Science, 91(5):1751-1758.

Yu Xia, Wei Chen*, Jianxin Zhao, Fengwei Tian, Hao Zhang*, Xiaolin Ding. 2007. Construction of a new food-grade expression system for Bacillus subtilis based on theta replication plasmids and auxotrophic complementation. Applied Microbiology and Biotechnology, 76(3):643-650.

Yu Xia, Wei Chen, Xiaoyan Fu, Hao Zhang*, Sheng Yang*, 2005. Xiaolin Ding. Construction of an integrative food-grade expression system for Bacillus subtilis. Food Research International, 38(3):251-256.

食品安全危害物检测和控制关键技术与装备. 中国商业联合会, 科技进步奖，特等奖, 2021（排第1）

水产品加工过程中危害物的识别检测与控制技术研发. 中国轻工业联合会，科技进步奖, 三等奖, 2020（排第4）

食品安全危害物适配体SELEX筛选体系及纳米生物界面组装研究. 教育部，自然科学技术奖, 二等奖, 2017（排第5）

食源性致病菌/生物毒素纳米生物传感检测技术研究及应用. 中国轻工业联合会，科技进步奖, 二等奖, 2014（排第3）

食源性致病菌/生物毒素纳米生物传感检测技术研究及应用. 中国食品科学技术学会，科技进步奖, 三等奖, 2014（排第5）

高温乳糖酶的研究开发与应用. 中国商业联合会科学技术奖，科技进步奖，一等奖，2012（排第5）

信号肽编码序列库的构建及耐热乳糖酶的分泌. 中国食品科学技术学会食品机械分会，优秀论文奖, 一等奖, 2011（排第1）

第八届全国大学生生命科学竞赛（“真菌毒素降解酶的异源表达、固定化和酶制剂工艺研究”，全国A2类竞赛三等奖）指导教师（排1），2023年

“荣智权奖教金”，无锡市海外联谊会，2022年

夏雨，吴梓凤，何瑞，秋杨煜，程倩倩，王周平. 一种能降解玉米赤霉烯酮的水解酶的突变体构建方法及其应用. 发明专利，中国（ZL 202110789525.8）

夏雨，何瑞，吴梓凤，王周平，秋杨煜，程倩倩. 一种能降解黄曲霉毒素B₁的锰过氧化物酶的突变体构建方法及其应用. 发明专利，中国（ZL 202110958714.3）

夏雨，吴梓凤，秋杨煜，何瑞，程倩倩，王周平. 一种能同时降解黄曲霉毒素B₁和玉米赤霉烯酮的融合酶的突变体构建方法及其应用. 发明专利，中国（ZL 202110800161.9）

夏雨，孙莹，吴梓凤，王周平，刘祖河，刘琦，吕涛. 一种猪粪发酵制备有机肥的方法. 发明专利，中国（CN 202010383739.0）

夏雨，孙莹，吴梓凤，吴世嘉，刘祖河，刘琦，王周平. 一种能降解黄曲霉毒素B₁的锰过氧化物酶及其应用. 发明专利，中国（ZL 202010034601.X）

夏雨，茅菁菁，王周平，刘祖河，刘琦. 一种基因工程菌株实现全细胞转化合成L-苯乳酸的方法. 发明专利，中国（ZL 201911044513.5）

夏雨，贺莉莉，王周平，马小媛，吴世嘉，段诺. 一种可降解亚硝酸盐的副干酪乳杆菌及其特性研究. 发明专利，中国（ZL 201711468925.9）

Wang ZP, Chen XJ, Gu HJ, Xia Y, Wu SJ, Duan N, Ma XY. Specific oligonucleotide aptamer for the identification of T-2 toxin. 发明专利，美国（US 9,856,482 B2. 2018）

王周平，叶华，段诺，吴世嘉，夏雨，马小媛. 一种特异识别细菌脂多糖的广谱核酸适配体及其定向筛选方法. 发明专利，中国（ZL 201710168491.4）

王周平，巩文慧，段诺，吴世嘉，夏雨，马小媛. 一组高特异识别盐酸克伦特罗，沙丁胺醇和莱克多巴胺的寡核苷酸适配子. 发明专利，中国（ZL 201610128853.2）

王周平，陈秀娟，顾华杰，夏雨，吴世嘉，段诺，马小媛. 一种特异识别T-2毒素的寡核苷酸适配体. 发明专利，中国（ZL 201410357649.9）

王周平，王鑫，段诺，吴世嘉，夏雨，马小媛. 一组特异性识别无乳链球菌的寡核苷酸适配子. 发明专利，中国（ZL 201210570202.0）

王周平，王鑫，段诺，吴世嘉，夏雨，马小媛. 一组特异性识别化脓链球菌的寡核苷酸适配子. 发明专利，中国（ZL 201210570205.4）

王周平，巩文慧，段诺，吴世嘉，夏雨，马小媛，郭晓飞. 一组特异识别宋内氏志贺氏菌的寡核苷酸适配子. 发明专利，中国（ZL 201410524006.9）

陈卫，夏雨，张灏，陈海琴，赵建新，田丰伟，刘小鸣. 一种双精氨酸途径蛋白质分泌载体的构建方法及其应用. 发明专利，中国（ZL 200810180274）

陈卫，田丰伟，姜俊，张灏，赵建新，刘小鸣，卢蓉蓉，夏雨. 一种具有降低牛乳中β-乳球蛋白抗原性能力的干酪乳杆菌与用途. 发明专利，中国（ZL 200810182817.X）

本科生课程：《食品微生物学》、《食品微生物学实验》

本科生培养：指导本科生专业综合训练、本科生工厂实习、本科生毕业实习、本科毕业设计（论文）指导、大学生创新训练计划、大学生国家级竞赛、大学生产品设计大赛等

研究生课程：《食品安全风险与评估》

研究生培养：独立指导硕士研究生20名；参与指导硕士研究生26名。

研究生培养：独立指导硕士研究生20名；参与指导硕士、博士研究生26名。

欢迎对食品生物技术、微生物生物工程和食品安全质量控制感兴趣的推免生、本科生报考我的研究生。

更新日期：2024年11月