倪大伟，江南大学食品学院副研究员，硕士生导师，主要从事食品酶工程。功能糖生物制造及高效蛋白表达系统等研究。主持国家自然科学基金青年基金、“十四五”国家重点研发计划子课题、江苏省自然科学青年基金等纵向项目5项；主持或参与企业横向5项。以第一/通讯作者在Bioresour Technol、Trends Food Sci Tech、Biotechnol Adv、J Agric Food Chem、Food Chem等期刊发表SCI论文40余篇、参编英文书1部。
教育背景：
2019.09-2023.01，江南大学，食品科学与工程，博士
2021.10-2022.10，首尔国立大学，化学与生物工程系，博士生联合培养
2016.09-2019.06，江南大学，食品科学与工程，硕士
2012.09-2016.06，内蒙古大学，食品质量与安全，学士
1.国家自然科学基金青年基金（22308118），2024.01-2026.12，主持。
2.“十四五”国家重点研发计划子课题（2023YFF1103604），2024.01-2027.12，主持。
3.“十四五”国家重点研发计划子课题（2024YFF1106303/002），2024.12-2027.11，主持。
4.江苏省自然科学基金青年基金（BK20231045），2023.09-2026.08，主持。
5.山东省博士后创新项目（SDCX-ZG-202502110），2025.07-2027.06，主持。
1.Hangbin He, Yang Yang, Qiang Wei, Xiaoyong Liu, Wei Xu, Wenli Zhang, Dawei Ni*, Wanmeng Mu. Enhanced levansucrase expression in Bacillus subtilis via regulatory element optimization for high-yield lactosucrose production from sucrose and lactose. Bioresource Technology, 2026, 456: 134954.
2. Qian Lin, Yuanlin Liu, Wenbo Zhang, Liping Qiao, Yingying Zhu, Dawei Ni*, Wanmeng Mu. High-Efficiency N-acetylneuraminic acid biosynthesis in plasmid-free Escherichia coli MG1655. Bioresource Technology, 2026, 452: 134585.
3.Zhaolin Huang, Jiajun Chen, Guocong Luo, Wei Xu, Wenli Zhang, Dawei Ni*, Wanmeng Mu.Structure-guided tunnel engineering to improve the catalytic efficiency of a cellobiose 2-epimerase for efficient lactulose synthesis. Journal of Agricultural and Food Chemistry, 2025, 73: 26846-26855.
4. Junya Yang, Wei Xu, Xiaoyong Liu, Lingxiu Wang, Yuze Li, Rongrong Ma, Wenli Zhang, Dawei Ni*, Wanmeng Mu. Nonclassical secretion and translational optimization for enhancing alginate lyase expression in Bacillus subtilis. Journal of Agricultural and Food Chemistry, 2025, 73: 17147-17155.
5. Yehong Cao, Yihan Chen, Wei Xu, Yingying Zhu, Wenli Zhang, Dawei Ni*, Wanmeng Mu.Recent advances on health effects and biological production of functional monosaccharide d-mannose. Trends in Food ScienceandTechnology. 2025, 163: 105137.
6. Shenxi Zhao, Jiajun Chen, Yuhan Wei, Wei Xu, Wenli Zhang, Dawei Ni*, Wanmeng Mu. Characterization of a tagatose 4-epimerase and optimizing its expression for efficient D-tagatose bioconversion from fructose. International Journal of Biological Macromolecules. 2025, 311: 143722.
7.Dawei Ni, Zhaolin Huang, Shuqi Zhang, Xiaodong Hou, Wei Xu, Wenli Zhang, Yijian Rao, and Wanmeng Mu. Structure-guided tunnel engineering to reveal the molecular basis of sugar chain extension of inulosucrase. Journal of Agricultural and Food Chemistry, 2025, 73: 16454-16467.
8.Dawei Ni, Shuqi Zhang, Zhaolin Huang, Xiaoyong Liu, Wei Xu, Wenli Zhang, and Wanmeng Mu. Multistrategy engineering of an inulosucrase to enhance the activity and thermostability for efficient production of microbial inulin. Journal of Agricultural and Food Chemistry 2024, 72: 18100-18109.
9.Dawei Ni, Shuqi Zhang, Xiaoyong Liu, Yingying Zhu, Wei Xu, Wenli Zhang, Wanmeng Mu.Production, effects, and applications of fructans with various molecular weights. Food Chemistry, 2024, 437: 137895.
10.Dawei Ni, Ziwei Chen, Yuqing Tian, Wei Xu, Wenli Zhang, Byung-Gee Kim, Wanmeng Mu,Comprehensive utilization of sucrose resources via chemical and biotechnological processes: A review. Biotechnology Advances, 2022, 60: 107990.
中国商业联合会科技进步特等奖；
中国石油和化学工业联合会科技进步三等奖
1.沐万孟；张文立；倪大伟；徐炜；张书琦，一种热稳定性和酶活提高的菊糖蔗糖酶突变体，ZL202110615300.0
2.沐万孟；张文立；倪大伟；徐炜，一种产蔗果三糖的菊糖蔗糖酶突变体，ZL202110613892.2
3.沐万孟；张文立；倪大伟；江波；张涛，一种菊糖蔗糖酶突变体及其应用，ZL201910682366.4
酶工程原理与酶应用技术，食品合成生物学
