代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.

代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.

代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.

代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.

代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.

代表性学术论文：

1.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets. Trends in Analytical Chemistry, 2025, 184, 118130.

2.Zhuowen Deng, Yong-Huan Yun, Nuo Duan, Shijia Wu^*.Artificial intelligence algorithms-assisted biosensors in the detection of foodborne pathogenic bacteria: Recent advances and future trends.Trends in Food Science & Technology, 2025, 161, 105072.

3.Zhiyuan Ning, Yingming Zhang, Shikun Zhang, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Cellular fluorescence imaging technology for food risk and function evaluation. Trends in Food Science & Technology, 2024, 153, 104742.

4.Shikun Zhang, Yingming Zhang, Zhiyuan Ning, Mengxia Duan, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Design and application of microfluidics in aptamer SELEX and Aptasensors. Biotechnology Advances, 2024, 77, 108461.

5.Jiajun Wu, Xianfeng Lin, Jin Li, Ziyu Lv, Nuo Duan, Zhouping Wang, ShijiaWu^*. Dual-color nanospheres based on aggregation-induced emission and catalytic hairpin assembly for simultaneous imaging of acrylamide and miR-21 in living cells. Journal of Hazardous Materials, 2024, 462, 132815.

6.Xianfeng Lin, Changxin Li, Xiangyi Meng, Wenyan Yu, Nuo Duan, Zhouping Wang, Shijia Wu^*. CRISPR-Cas12a-mediated luminescence resonance energy transfer aptasensing platform for deoxynivalenol using gold nanoparticle-decorated Ti₃C₂T_XMXene as the enhanced quencher. Journal of Hazardous Materials, 2022, 433, 128750.

7.Chuxian He, You Zhou, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deoxynivalenol-induced cell apoptosis monitoring using a cytochrome c-specific fluorescent probe based on a photoinduced electron transfer reaction. Journal of Hazardous Materials, 2021, 415, 125638.

8.Jin Li, Xianfeng Lin, Jiajun Wu, Dichen Ying, Nuo Duan, Zhouping Wang, Shijia Wu^*. Multifunctional magnetic composite nanomaterial for Colorimetric-SERS Dual-Mode detection and photothermal sterilization of Vibrio parahaemolyticus. Chemical Engineering Journal, 2023, 477, 147113.

9.Lixin Kang, Jia Wang, Xianfeng Lin, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. A Full-Color Carbon Quantum Dots Fluorescence Sensing Array Combined with Machine Learning for Rapid Bacterial Detection and Classification. Advanced Healthcare Materials, 2025, e02916.

10.Qinyan Xu, Xiaoyao Wang, Zepeng Gu, Nuo Duan, Sunming Jiang, Shijia Wu^*, Wenbo Yuan^*.An electrochemical/colorimetric sensor for 5-methyltetrahydrofolate based on a screened specific aptamer and DNA walker-driven CRISPR/Cas12a cascade amplification. Biosensors and Bioelectronics, 2025, 289, 117931.

11.Shikun Zhang, Zhiyuan Ning, Yingming Zhang, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer. Biosensors and Bioelectronics, 2025, 271, 117038.

12.Jiaqi Feng, Chunxia Lu, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Changbin Liu,Shijia Wu^*. A portable microfluidic chip-based fluorescent and colorimetric aptasensor combining recombinase polymerase amplification for bovine pregnancy-associated glycoproteins detection. Biosensors and Bioelectronics, 2025, 270, 116981.

13.Lixin Kang, Jiajun Wu, Xianfeng Lin, Jin Li, Nuo Duan, Zhouping Wang, Shijia Wu^*. Detection and simultaneous imaging of acrylamide, miR-21 and miR-221 based on multicolor aggregation-induced emission nanoparticles and DNAzyme walker. Biosensors and Bioelectronics, 2024, 264, 116628.

14.Nuo Duan, Yuting Chang, Tingting Su, Xinyue Zhang, Minghui Lu, Zhouping Wang, Shijia Wu^*. Generation of a specific aptamer for accurate detection of sarafloxacin based on fluorescent/colorimetric/SERS triple-readout sensor. Biosensors&Bioelectronics, 2024, 249, 116022.

15.Jiajia Lv, Sen Zhao,Shijia Wu^*, Zhouping Wang^*. Upconversion nanoparticles grafted molybdenum disulfide nanosheets platform for microcystin-LR sensing. Biosensors & Bioelectronics, 2017, 90, 203-209.

16.Shikun Zhang, Xianfeng Lin, Zepeng Gu, Lixin Kang, Yingming Zhang, Jun Sun, Nuo Duan, Zhouping Wang, Ruijie Deng, Shijia Wu^*. Machine learning assisted CRCA multi-color fluorescent droplet imaging for high-sensitivity simultaneous detection of Maillard hazards. iScience, 2025, 28, 9, 113212.

17.Xiaoyao Wang, Qinyan Xu, Zepeng Gu, Yingming Zhang, Shikun Zhang, Nuo Duan, Zhouping Wang, Shijia Wu^*. High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in ColorimetricSERS Dual-Mode Detection. Analytical Chemistry, 2025,10.1021/acs.analchem.5c03609.

18.Lixin Kang, Xianfeng Lin, Jiaqi Feng, Mengxia Duan, Nuo Duan, Zhouping Wang, Shijia Wu^*. Machine Learning-Assisted Multiplexed Fluorescence-LabeledmiRNAs Imaging Decoding for Combined Mycotoxins ToxicityAssessment. Analytical Chemistry, 2025, 97, 14, 8001-8010.

19.Xianfeng Lin, Lixin Kang, Jiaqi Feng, Nuo Duan, Zhouping Wang, Shijia Wu^*. Deep Learning-Assisted Fluorescence Single-Particle Detection ofFumonisin B₁Powered by Entropy-Driven Catalysis and Argonaute. Analytical Chemistry, 2025, 97, 7, 4066-4074.

20.Wenyan Yu, Lixin Kang, Xianfeng Lin, Nuo Duan, Dichen Ying, Zhouping Wang, andShijia Wu^*. Deoxynivalenol (DON)-Triggered Dual-Color Composite Probe Based on Gold Nanoclusters for Simultaneous Imaging of DON and miR-34a in Living Cells. Analytical Chemistry, 2023, 95, 50, 18611-18618.

21.Shijia Wu, Nuo Duan, Shi Zhao, Congcong Fang, Zhouping Wang^*. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels. Analytical Chemistry, 2014, 86,6, 3100-3107.

22.Zepeng Gu, Qinyan Xu, Xiaoyao Wang, Xianfeng Lin, Nuo Duan, Zhouping Wang,Shijia Wu^*. Food Freshness Prediction Platform Utilizing Deep Learning-BasedMultimodal Sensor Fusion of Volatile Organic Compounds andMoisture Distribution.ACS Sensors, 2025, 10, 4, 3091-3100.

23.Xinyu Tong, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu^*. Laser-Printed Paper-Based Microfluidic Chip Based on a Multicolor Fluorescence Carbon Dot Biosensor for Visual Determination of Multiantibiotics in Aquatic Products.ACS Sensors, 2022, 7, 12, 3947-3955.

24.Xianfeng Lin, Jin Li, Jiajun Wu, Kaixi Guo, Nuo Duan, Zhouping Wang, Shijia Wu^*. Fe-Co-Based Metal-Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁. ACS Applied Materials & Interfaces, 2024, 16, 9, 11809-11820.

25.Xuhan Xia, Ting Zhang, Sha Deng, Junbo Chen,Shijia Wu^*, Chuxian He, Kaxixiang Zhang, Ruijie Deng*, Qiang He. Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry & Engineering, 2020, 8, 26, 9920-9925.

26.Jiaqi Feng, Jin Li, Xianfeng Lin, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. A polydopamine coated magnetic spiral switchable composite material for photothermal sterilization and dual-color fluorescence detection of food-borne pathogens. Sensors and Actuators: B. Chemical, 2025, 425, 136935.

27.Xianfeng Lin, Kaixi Guo, Zhongxiang Wang, Lixin Kang, Nuo Duan, Zhouping Wang, Shijia Wu^*. Construction of aptamer-gated colorimetric sensor based on MIL-acetylcholinesterase to detect acrylamide in food. Sensors and Actuators B: Chemical, 2024, 418, 136338.

28.Xinyu Tong, Xianfeng Lin, Nuo Duan, Ziyu Lv, Zhouping Wang,Shijia Wu^*. A novel colorimetric and fluorescent dual-mode 3D paper-based microfluidic aptasensor for the point-of-care detection of sulfadimethoxine. Sensors and Actuators: B. Chemical, 2023, 397, 134691.

29.Shijia Wu, Nuo Duan, Xiaoyuan Ma, Yu Xia, Ye Yu, Zhouping Wang^*, Hongxin Wang. Simultaneous detection of enterovirus 71 and coxsackievirus A16 using dual-colour upconversion luminescent nanoparticles as lables. Chemical Communications, 2012, 48, 40, 4866-4868.

30.Yingming Zhang, Shikun Zhang, Zhiyuan Ning, Xianfeng Lin, Nuo Duan, Zhouping Wang, Shijia Wu. Development of an Automated Capture-SELEX Device for EfficientScreening ofβ‑Conglycinin Aptamer. Journal of Agricultural and Food Chemistry, 2024, 72, 50, 28148-28156.

31.Nuo Duan, Kexin Ren, Chen Lyu, Zhouping Wang, Shijia Wu^*. Discovery and Optimization of an Aptamer and Its Sensing Ability to Amantadine Based on SERS via Binary Metal Nanoparticles. Journal of Agricultural and Food Chemistry, 2022, 70, 46, 14805-14815.

32.Lehan Zhao, Xianfeng Lin, Nuo Duan, Imran Mahmood Khan, Zhouping Wang, Shijia Wu^*. A sensitive fluorescent assay based on gold-nanoclusters coated on molecularly imprinted covalent organic frameworks and its application in malachite green detection. Food Chemistry, 2023, 410, 135425.

33.Xianfeng Lin, Changxin Li, Xinyu Tong, Nuo Duan, Zhouping Wang, Shijia Wu^*. A portable paper-based aptasensor for simultaneous visual detection of two mycotoxins in corn flour using dual-color upconversion nanoparticles and Cu-TCPP nanosheets. Food Chemistry, 2023, 404, 134750.